WISE Uranium Project - FAQ Depleted Uranium in Urine of Soldiers
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Distribution of uranium in rats implanted with depleted uranium pellets.
During the Persian Gulf War, soldiers were injured with depleted uranium (DU) fragments. To assess the potential health risks associated with chronic exposure to DU, Sprague Dawley rats were surgically implanted with DU pellets at 3 dose levels (low, medium and high). Biologically inert tantalum (Ta) pellets were used as controls. At 1 day and 6, 12, and 18 months after implantation, the rats w...
متن کاملEstimating the lung burden from exposure to aerosols of depleted uranium.
Following exposure to aerosols of depleted uranium (DU), biological samples show the presence of a synthetic mixture of natural uranium and DU. By partitioning the uranium in the 24-h urine sample along the isotopic fractions of natural uranium and DU, one can study the kinetics of these subpopulations independently. A linear model is developed to estimate the lung burden of DU from measurement...
متن کاملA Review on Toxicodynamics of Depleted Uranium
Depleted uranium (DU) is an important by product in uranium enrichment process. Due toits applications in civilian and also military activity, DU emerged as environmental pollutant.The exposure to DU can occur via external or internal pathways. In external exposure, mainlybeta radiation from the decay products contributes to DU toxicity. Internal exposure to DUis more im...
متن کاملUranium in Urine: Quantification and Isotope Ratio Determination
While the quantification of uranium is therefore demanding in the diluted sample, uranium isotope ratio determination requires the ultimate in instrumental performance as good precisions for large isotope ratios are required at low concentrations. The abundances of the three naturally occurring U isotopes are shown in Table 1, together with the 234U/238U and 235U/238U ratios. The nuclear indust...
متن کاملMitochondrial Toxicity of Depleted Uranium: Protection by Beta-Glucan
Considerable evidence suggests that mitochondrial dysfunction contributes to the toxicity of uranyl acetate (UA), a soluble salt of depleted uranium (DU). We examined the ability of the two antioxidants, beta-glucan and butylated hydroxyl toluene (BHT), to prevent UA-induced mitochondrial dysfunction using rat-isolated kidney mitochondria. Beta-glucan (150 nM) and BHT (20 nM) attenuated UA-indu...
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